National pbm bulletin - Pharmacy Benefits Management Services
Apr 18, 2016. I. ISSUE. FDA revises warnings concerning metformin use in certain patients with renal impairment and suggests using a new measurement for. This appendix explains both the original and updated US Food and Drug Administration's safety warnings in relation to the use of metformin. May 24, 2016. FDA's recent decision to update labeling information for metformin use in patients with mild to moderate renal impairment is welcome news for.
FDA Loosens Restrictions on Metformin Use in Patients with Mild-to.
Apr 11, 2016. By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH Metformin may be safely used in all patients with mild renal. Nov 1, 2016. FDA eliminated the heart failure contraindication in response to 2 observational studies.1. cause metformin is a generic drug, it lacked a pharmaceutical industry sponsor to. Administration to Change Prescribing Guidelines.