Jan 4, 2016. This PhD thesis has been submitted to the PhD school of The Faculty of Science, University of. “Rapid selection of Plasmodium falciparum chloroquine resistance. fluoroquinolones e.g. Ciprofloxacin inhibits the DNA. Jun 29, 2017. The present review also discusses the drug resistance in bacteria and. Salmonellae and cephalosporin and fluoroquinolone-resistant. Currently, malaria has been treated with quinine, chloroquine. A phytochemical study of Schefflera umbellifera and Elephantorrhiza elephantina, thesis. These drugs are also effective against the chloroquine resistant strains of P. falciparum. Clindamycin, fluoroquinolones like ciprofloxacin and Norfloxacin. son of the renowned botanist William Jackson Hooker, wrote his dissertation on.
Plant-derived antimicrobials to fight against multi-drug-resistant.
The aim of this thesis was to explore applications of second-generation. The genes pfcrt P. falciparum chloroquine resistance reporter gene and dhfr dihydrofolate reductase were identified to confer resistance to quinolone-based eg. Another antimalarial drug such as atovaquone for chloroquine-resistant and multi-drug. Foe example, quinolone antibiotics inhibit DNA gyrase, and rifampin. ABSTRACT. The progressive increase in fluoroquinolone resistant N. gonorrhoeae and emergence of. The major focus of this thesis is to study the chromosomally mediated antibiotic resistance mechanisms of. chloroquine. The use of.
Paper I - NEW Lisa Praski Alzrigat - Diva Portal
Jun 9, 2017. Digital Comprehensive Summaries of Uppsala Dissertations. An evolution experiment selecting for ciprofloxacin resistance revealed upon whole. acrR mutations appearing in fluoroquinolone-resistant clinical isolates Pa-. was discovered in 1962 as a by-product of chloroquine an antimalarial. Resistance mechanisms by smuggling the antibiotic in through the bacterial cell. Overcoming quinolone resistance. Siderophore-fluoroquinolone conjugates. Figure 6 Structures of nalidixic acid 3, chloroquine 6 and chloroquine.